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Host Cell Contaminant Testing: Ensuring Biopharmaceutical Safety
Host cell contaminant testing is a critical quality control measure in biopharmaceutical manufacturing. During the production of biologic drugs, host cells such as bacteria or mammalian cells are used to produce therapeutic proteins. These cells can leave behind residual impurities that must be detected and removed.
Testing focuses on identifying host cell proteins, DNA, and other contaminants that could affect product safety or efficacy. Sensitive analytical methods are used to ensure that impurity levels remain within acceptable limits before products reach patients.
Effective host cell contaminant testing supports regulatory compliance and builds confidence in biologic therapies. It helps manufacturers verify that purification processes are working as intended and that final products meet strict quality standards.
As biologic drugs become more complex, robust testing strategies are increasingly important. Continuous improvement in analytical techniques enhances detection capabilities and reliability.
Host cell contaminant testing plays a vital role in protecting patient safety. By…





